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BPS Bioscience brd4 bd1 bd2 tr fret assay kit
Investigational drugs—bromodomain 4 <t>(BRD4)</t> inhibitors.
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Investigational drugs—bromodomain 4 <t>(BRD4)</t> inhibitors.
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Image Search Results


Investigational drugs—bromodomain 4 (BRD4) inhibitors.

Journal: Molecules

Article Title: SAR by Space: Enriching Hit Sets from the Chemical Space

doi: 10.3390/molecules24173096

Figure Lengend Snippet: Investigational drugs—bromodomain 4 (BRD4) inhibitors.

Article Snippet: All TR-FRET assays and IC 50 measurements were performed using BRD4 (BD1+BD2) TR-FRET assay kit from BPS Bioscience ( www.bpsbioscience.com ) following the standard procedure [ ].

Techniques:

Known BRD4 inhibitors—analogs of the series identified in this work.

Journal: Molecules

Article Title: SAR by Space: Enriching Hit Sets from the Chemical Space

doi: 10.3390/molecules24173096

Figure Lengend Snippet: Known BRD4 inhibitors—analogs of the series identified in this work.

Article Snippet: All TR-FRET assays and IC 50 measurements were performed using BRD4 (BD1+BD2) TR-FRET assay kit from BPS Bioscience ( www.bpsbioscience.com ) following the standard procedure [ ].

Techniques:

Most active  BRD4  inhibitors identified after  TR-FRET  (time-resolved fluorescence energy transfer) assay.

Journal: Molecules

Article Title: SAR by Space: Enriching Hit Sets from the Chemical Space

doi: 10.3390/molecules24173096

Figure Lengend Snippet: Most active BRD4 inhibitors identified after TR-FRET (time-resolved fluorescence energy transfer) assay.

Article Snippet: All TR-FRET assays and IC 50 measurements were performed using BRD4 (BD1+BD2) TR-FRET assay kit from BPS Bioscience ( www.bpsbioscience.com ) following the standard procedure [ ].

Techniques: Fluorescence